Double-edged-sword effect of IL-1β on the osteogenesis of periodontal ligament stem cells via crosstalk between the NF-κB, MAPK and BMP/Smad signaling pathways

Microenvironmental conditions can interfere with the functional role and differentiation of mesenchymal stem cells (MSCs). Recent studies suggest that an inflammatory microenvironment can significantly impact the osteogenic potential of periodontal ligament stem cells (PDLSCs), but the precise effec...

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Detalles Bibliográficos
Autores principales: Mao, C-y, Wang, Y-g, Zhang, X, Zheng, X-y, Tang, T-t, Lu, E-y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973347/
https://www.ncbi.nlm.nih.gov/pubmed/27415426
http://dx.doi.org/10.1038/cddis.2016.204

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