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Granzyme M has a critical role in providing innate immune protection in ulcerative colitis

Inflammatory bowel disease (IBD) is an immunoregulatory disorder, associated with a chronic and inappropriate mucosal immune response to commensal bacteria, underlying disease states such as ulcerative colitis (UC) and Crohn's disease (CD) in humans. Granzyme M (GrzM) is a serine protease expre...

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Detalles Bibliográficos
Autores principales: Souza-Fonseca-Guimaraes, F, Krasnova, Y, Putoczki, T, Miles, K, MacDonald, K P, Town, L, Shi, W, Gobe, G C, McDade, L, Mielke, L A, Tye, H, Masters, S L, Belz, G T, Huntington, N D, Radford-Smith, G, Smyth, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973354/
https://www.ncbi.nlm.nih.gov/pubmed/27441655
http://dx.doi.org/10.1038/cddis.2016.215