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Granzyme M has a critical role in providing innate immune protection in ulcerative colitis
Inflammatory bowel disease (IBD) is an immunoregulatory disorder, associated with a chronic and inappropriate mucosal immune response to commensal bacteria, underlying disease states such as ulcerative colitis (UC) and Crohn's disease (CD) in humans. Granzyme M (GrzM) is a serine protease expre...
Autores principales: | Souza-Fonseca-Guimaraes, F, Krasnova, Y, Putoczki, T, Miles, K, MacDonald, K P, Town, L, Shi, W, Gobe, G C, McDade, L, Mielke, L A, Tye, H, Masters, S L, Belz, G T, Huntington, N D, Radford-Smith, G, Smyth, M J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973354/ https://www.ncbi.nlm.nih.gov/pubmed/27441655 http://dx.doi.org/10.1038/cddis.2016.215 |
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