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Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit

The molecular pathways underlying tumor suppression are incompletely understood. Here, we identify cooperative non-cell-autonomous functions of a single gene that together provide a novel mechanism of tumor suppression in basal keratinocytes of zebrafish embryos. A loss-of-function mutation in atp1b...

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Detalles Bibliográficos
Autores principales: Hatzold, Julia, Beleggia, Filippo, Herzig, Hannah, Altmüller, Janine, Nürnberg, Peter, Bloch, Wilhelm, Wollnik, Bernd, Hammerschmidt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973367/
https://www.ncbi.nlm.nih.gov/pubmed/27240166
http://dx.doi.org/10.7554/eLife.14277