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Engineered AAV vectors for improved central nervous system gene delivery
Adeno-associated viruses (AAV) are non-pathogenic members of the Parvoviridae family that are being harnessed as delivery vehicles for both basic research and increasingly successful clinical gene therapy. To address a number of delivery shortcomings with natural AAV variants, we have developed and...
Autores principales: | A Kotterman, Melissa, Schaffer, David V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973602/ https://www.ncbi.nlm.nih.gov/pubmed/27606332 http://dx.doi.org/10.1080/23262133.2015.1122700 |
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