An (R)‐Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines

Although the range of biocatalysts available for the synthesis of enantiomerically pure chiral amines continues to expand, few existing methods provide access to secondary amines. To address this shortcoming, we have over‐expressed the gene for an (R)‐imine reductase [(R)‐IRED] from Streptomyces sp....

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Detalles Bibliográficos
Autores principales: Hussain, Shahed, Leipold, Friedemann, Man, Henry, Wells, Elizabeth, France, Scott P., Mulholland, Keith R., Grogan, Gideon, Turner, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973613/
https://www.ncbi.nlm.nih.gov/pubmed/27547270
http://dx.doi.org/10.1002/cctc.201402797

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