Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease

AIMS: Cerebellar ataxia is common in patients with mitochondrial disease, and despite previous neuropathological investigations demonstrating vulnerability of the olivocerebellar pathway in patients with mitochondrial disease, the exact neurodegenerative mechanisms are still not clear. We use quanti...

Descripción completa

Detalles Bibliográficos
Autores principales: Chrysostomou, Alexia, Grady, John P., Laude, Alex, Taylor, Robert W., Turnbull, Doug M., Lax, Nichola Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973693/
https://www.ncbi.nlm.nih.gov/pubmed/26337858
http://dx.doi.org/10.1111/nan.12282

Ejemplares similares

Ejemplares similares