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Assessing the Delivery of Molecules to the Mitochondrial Matrix Using Click Chemistry

Mitochondria are central to health and disease, hence there is considerable interest in developing mitochondria‐targeted therapies that require the delivery of peptides or nucleic acid oligomers. However, progress has been impeded by the lack of a measure of mitochondrial import of these molecules....

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Detalles Bibliográficos
Autores principales: Hoogewijs, Kurt, James, Andrew M., Smith, Robin A. J., Gait, Michael J., Murphy, Michael P., Lightowlers, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973694/
https://www.ncbi.nlm.nih.gov/pubmed/27124570
http://dx.doi.org/10.1002/cbic.201600188