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Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production

Soluble flagellin (sFliC) from Salmonella Typhimurium (STm) can induce a Th2 response to itself and coadministered antigens through ligation of TLR5. These properties suggest that sFliC could potentially modulate responses to Th1 antigens like live STm if both antigens are given concurrently. After...

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Detalles Bibliográficos
Autores principales:	Flores‐Langarica, Adriana, Bobat, Saeeda, Marshall, Jennifer L., Yam‐Puc, Juan Carlos, Cook, Charlotte N., Serre, Karine, Kingsley, Robert A., Flores‐Romo, Leopoldo, Uematsu, Satoshi, Akira, Shizuo, Henderson, Ian R., Toellner, Kai M., Cunningham, Adam F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Immunity to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973836/ https://www.ncbi.nlm.nih.gov/pubmed/26036767 http://dx.doi.org/10.1002/eji.201545564

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