Mycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism: Dispensability of Phosphorylation, Cooperativity and Essentiality of α10 Helix

DevR/DosR is a well-characterized regulator in Mycobacterium tuberculosis which is implicated in various processes ranging from dormancy/persistence to drug tolerance. DevR induces the expression of an ~48-gene dormancy regulon in response to gaseous stresses, including hypoxia. Strains of the Beiji...

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Detalles Bibliográficos
Autores principales: Sharma, Saurabh, Tyagi, Jaya Sivaswami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973870/
https://www.ncbi.nlm.nih.gov/pubmed/27490491
http://dx.doi.org/10.1371/journal.pone.0160723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973870/
https://www.ncbi.nlm.nih.gov/pubmed/27490491
http://dx.doi.org/10.1371/journal.pone.0160723

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