Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

Human breast cancer susceptibility gene, BRCA2, encodes a 3418-amino acid protein that is essential for maintaining genomic integrity. Among the proteins that physically interact with BRCA2, Partner and Localizer of BRCA2 (PALB2), which binds to the N-terminal region of BRCA2, is vital for its funct...

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Detalles Bibliográficos
Autores principales: Hartford, Suzanne A., Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C., Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973925/
https://www.ncbi.nlm.nih.gov/pubmed/27490902
http://dx.doi.org/10.1371/journal.pgen.1006236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973925/
https://www.ncbi.nlm.nih.gov/pubmed/27490902
http://dx.doi.org/10.1371/journal.pgen.1006236

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