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RhoA Signaling and Synaptic Damage Occur Within Hours in a Live Pig Model of CNS Injury, Retinal Detachment

PURPOSE: The RhoA pathway is activated after retinal injury. However, the time of onset and consequences of activation are unknown in vivo. Based on in vitro studies we focused on a period 2 hours after retinal detachment, in pig, an animal whose retina is holangiotic and contains cones. METHODS: Un...

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Detalles Bibliográficos
Autores principales: Wang, Jianfeng, Zarbin, Marco, Sugino, Ilene, Whitehead, Ian, Townes-Anderson, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974026/
https://www.ncbi.nlm.nih.gov/pubmed/27472075
http://dx.doi.org/10.1167/iovs.16-19447

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