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Comparing Analytic Methods for Longitudinal GWAS and a Case-Study Evaluating Chemotherapy Course Length in Pediatric AML. A Report from the Children's Oncology Group
Regression analysis is commonly used in genome-wide association studies (GWAS) to test genotype-phenotype associations but restricts the phenotype to a single observation for each individual. There is an increasing need for analytic methods for longitudinally collected phenotype data. Several method...
Autores principales: | Vujkovic, Marijana, Aplenc, Richard, Alonzo, Todd A., Gamis, Alan S., Li, Yimei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974249/ https://www.ncbi.nlm.nih.gov/pubmed/27547214 http://dx.doi.org/10.3389/fgene.2016.00139 |
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