Cargando…

ACTH Antagonists

Adrenocorticotropin (ACTH) acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R), is unusual in that it is absolutely dependent on a small accessory prote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clark, Adrian John, Forfar, Rachel, Hussain, Mashal, Jerman, Jeff, McIver, Ed, Taylor, Debra, Chan, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974254/ https://www.ncbi.nlm.nih.gov/pubmed/27547198 http://dx.doi.org/10.3389/fendo.2016.00101

Ejemplares similares

Identification of a novel specific small-molecule melanocortin-2-receptor antagonist
por: Forfar, Rachel, et al.
Publicado: (2022)

From Bioinactive ACTH to ACTH Antagonist: The Clinical Perspective
por: Ghaddhab, Chiraz, et al.
Publicado: (2017)

Stability and Turnover of the ACTH Receptor Complex
por: Clark, Adrian J. L., et al.
Publicado: (2019)

The Potential of ACTH in the Genesis of Primary Aldosteronism
por: Funder, John W.
Publicado: (2016)

Effect of Novel Melanocortin Type 2 Receptor Antagonists on the Corticosterone Response to ACTH in the Neonatal Rat Adrenal Gland In Vivo and In Vitro
por: Nensey, Nasha K., et al.
Publicado: (2016)

ACTH Regulation of Adrenal SR-B1
por: Shen, Wen-Jun, et al.
Publicado: (2016)

ACTH Action on Messenger RNA Stability Mechanisms
por: Desroches-Castan, Agnès, et al.
Publicado: (2017)

Impact of ACTH Signaling on Transcriptional Regulation of Steroidogenic Genes
por: Ruggiero, Carmen, et al.
Publicado: (2016)

The Role of ACTH and Corticosteroids for Sepsis and Septic Shock: An Update
por: Annane, Djillali
Publicado: (2016)

Effects of Chronic ACTH Excess on Human Adrenal Cortex
por: Bertagna, Xavier
Publicado: (2017)

Non-Canonical Effects of ACTH: Insights Into Adrenal Insufficiency
por: Hasenmajer, Valeria, et al.
Publicado: (2021)

Sex Differences in Presentation but Not in Outcome for ACTH-Dependent Cushing's Syndrome
por: Broersen, Leonie H. A., et al.
Publicado: (2019)

Case Report: An Unusual Case of Ectopic ACTH Syndrome Caused by Mediastinal Paraganglioma
por: Li, Bo, et al.
Publicado: (2022)

Phase-Dependent Shifting of the Adrenal Clock by Acute Stress-Induced ACTH
por: Engeland, William C., et al.
Publicado: (2016)

Role of ACTH and Other Hormones in the Regulation of Aldosterone Production in Primary Aldosteronism
por: El Ghorayeb, Nada, et al.
Publicado: (2016)

Editorial: ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology
por: Gallo-Payet, Nicole, et al.
Publicado: (2017)

Comparative Effect of ACTH and Related Peptides on Proliferation and Growth of Rat Adrenal Gland
por: Lotfi, Claudimara Ferini Pacicco, et al.
Publicado: (2016)

Evaluation of plasma ACTH in the metyrapone test is insufficient for the diagnosis of secondary adrenal insufficiency
por: Papierska, Lucyna, et al.
Publicado: (2022)

Integration of Proteomics and Metabolomics Revealed Metabolite–Protein Networks in ACTH-Secreting Pituitary Adenoma
por: Feng, Jie, et al.
Publicado: (2018)

Effects of CRN04894, a Nonpeptide Orally Bioavailable ACTH Antagonist, on Corticosterone in Rodent Models of ACTH Excess
por: Fowler, Melissa A, et al.
Publicado: (2021)

Case Report: Three Rare Cases of Ectopic ACTH Syndrome Caused by Adrenal Medullary Hyperplasia
por: Cheng, Yu, et al.
Publicado: (2021)

Role of ACTH in the Interactive/Paracrine Regulation of Adrenal Steroid Secretion in Physiological and Pathophysiological Conditions
por: Lefebvre, Hervé, et al.
Publicado: (2016)

Circulating Plasma microRNA to Differentiate Cushing's Disease From Ectopic ACTH Syndrome
por: Belaya, Zhanna, et al.
Publicado: (2020)

Enhancing Cushing’s disease diagnosis: exploring the impact of desmopressin on ACTH gradient during BIPSS
por: de Almeida, Tobias Skrebsky, et al.
Publicado: (2023)

Dexamethasone affects human fetal adrenal steroidogenesis and subsequent ACTH response in an ex vivo culture model
por: Melau, Cecilie, et al.
Publicado: (2023)

Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3
por: Montero-Melendez, Trinidad, et al.
Publicado: (2016)

SAT-364 Nonpeptide Orally-Bioavailable ACTH Antagonists: Suppression of ACTH-Induced Corticosterone Secretion and Adrenal Hypertrophy in Rats
por: Kusnetzow, Ana, et al.
Publicado: (2019)

A novel TBX19 gene mutation in patients with isolated ACTH deficiency from distinct families with a common geographical origin
por: Charnay, Théo, et al.
Publicado: (2023)

Quantitative Ubiquitinomics Revealed Abnormal Ubiquitinated ATP7A Involved in Down-Regulation of ACTH in Silent Corticotroph Adenomas
por: Zhao, Sida, et al.
Publicado: (2022)

Adrenocorticotropic Hormone-Producing Paraganglioma With Low Plasma ACTH Level: A Case Report and Review of the Literature
por: Liu, Siyue, et al.
Publicado: (2020)

Pasireotide-Induced Shrinkage in GH and ACTH Secreting Pituitary Adenoma: A Systematic Review and Meta-Analysis
por: Mondin, Alessandro, et al.
Publicado: (2022)

ACTH-producing small cell neuroendocrine carcinoma from the gallbladder: a case report and literature review
por: Zhang, Xiaofang, et al.
Publicado: (2023)

ACTH Receptor (MC2R) Specificity: What Do We Know About Underlying Molecular Mechanisms?
por: Fridmanis, Davids, et al.
Publicado: (2017)

The High Prevalence of Testicular Adrenal Rest Tumors in Adult Men With Congenital Adrenal Hyperplasia Is Correlated With ACTH Levels
por: Mazzilli, Rossella, et al.
Publicado: (2019)

An Optimized Pathway for the Differential Diagnosis of ACTH-Dependent Cushing’s Syndrome Based on Low-Dose Dexamethasone Suppression Test
por: Chen, Kang, et al.
Publicado: (2021)

The Impact of ACTH on Peripheral Steroids Differs between Unilateral and Bilateral Primary Aldosteronism
por: Tezuka, Yuta, et al.
Publicado: (2021)

Alteration of ACTH and Cortisol Levels After Estradiol Valerate Treatment in a Male Subject With Gender Dysphoria: A Case Report
por: Anno, Takatoshi, et al.
Publicado: (2019)

Cortisol Co-Secretion and Clinical Usefulness of ACTH Stimulation Test in Primary Aldosteronism: A Systematic Review and Biases in Epidemiological Studies
por: Inoue, Kosuke, et al.
Publicado: (2021)

Case Report: A Challenging Localization of a Pulmonary Ectopic ACTH-Secreting Tumor in a Patient With Severe Cushing’s Syndrome
por: Serban, Andreea Liliana, et al.
Publicado: (2021)

Outcome of CRH stimulation test and overnight 8 mg dexamethasone suppression test in 469 patients with ACTH-dependent Cushing’s syndrome
por: Detomas, Mario, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r00bkmcfcempqe1se45v313biv