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Creatine target engagement with brain bioenergetics: a dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression
Major depressive disorder (MDD) often begins during adolescence and is projected to become the leading cause of global disease burden by the year 2030. Yet, approximately 40 % of depressed adolescents fail to respond to standard antidepressant treatment with a selective serotonin reuptake inhibitor...
Autores principales: | Kondo, Douglas G., Forrest, Lauren N., Shi, Xianfeng, Sung, Young-Hoon, Hellem, Tracy L., Huber, Rebekah S., Renshaw, Perry F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974294/ https://www.ncbi.nlm.nih.gov/pubmed/26907087 http://dx.doi.org/10.1007/s00726-016-2194-3 |
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