Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine

Zinc phosphide (Zn(3)P(2)/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepa...

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Detalles Bibliográficos
Autores principales: Oghabian, Zohreh, Afshar, Arefeh, Rahimi, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974425/
https://www.ncbi.nlm.nih.gov/pubmed/27525081
http://dx.doi.org/10.1002/ccr3.618
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author Oghabian, Zohreh
Afshar, Arefeh
Rahimi, Hamid Reza
author_facet Oghabian, Zohreh
Afshar, Arefeh
Rahimi, Hamid Reza
author_sort Oghabian, Zohreh
collection PubMed
description Zinc phosphide (Zn(3)P(2)/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepatotoxicity following accidental and intentional ZnP poisoning and successful management with N‐acetylcysteine (NAC).
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spelling pubmed-49744252016-08-12 Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine Oghabian, Zohreh Afshar, Arefeh Rahimi, Hamid Reza Clin Case Rep Case Reports Zinc phosphide (Zn(3)P(2)/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepatotoxicity following accidental and intentional ZnP poisoning and successful management with N‐acetylcysteine (NAC). John Wiley and Sons Inc. 2016-07-06 /pmc/articles/PMC4974425/ /pubmed/27525081 http://dx.doi.org/10.1002/ccr3.618 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Oghabian, Zohreh
Afshar, Arefeh
Rahimi, Hamid Reza
Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine
title Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine
title_full Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine
title_fullStr Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine
title_full_unstemmed Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine
title_short Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine
title_sort hepatotoxicity due to zinc phosphide poisoning in two patients: role of n‐acetylcysteine
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974425/
https://www.ncbi.nlm.nih.gov/pubmed/27525081
http://dx.doi.org/10.1002/ccr3.618
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AT afshararefeh hepatotoxicityduetozincphosphidepoisoningintwopatientsroleofnacetylcysteine
AT rahimihamidreza hepatotoxicityduetozincphosphidepoisoningintwopatientsroleofnacetylcysteine

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