Primary malignant myelomatous pleural effusion

Primary malignant myelomatous pleural effusion (PMMPE) occurs in less than 1% of patients with multiple myeloma and is diagnosed either by visualization of plasma cells on cytology or by positive flow cytometry. The presence of immature plasma cells characterized by high nucleus to cytoplasm ratio,...

Descripción completa

Detalles Bibliográficos
Autores principales: Mangla, Ankit, Agarwal, Nikki, Kim, George J., Catchatourian, Rosalind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974434/
https://www.ncbi.nlm.nih.gov/pubmed/27525090
http://dx.doi.org/10.1002/ccr3.634
_version_ 1782446542414675968
author Mangla, Ankit
Agarwal, Nikki
Kim, George J.
Catchatourian, Rosalind
author_facet Mangla, Ankit
Agarwal, Nikki
Kim, George J.
Catchatourian, Rosalind
author_sort Mangla, Ankit
collection PubMed
description Primary malignant myelomatous pleural effusion (PMMPE) occurs in less than 1% of patients with multiple myeloma and is diagnosed either by visualization of plasma cells on cytology or by positive flow cytometry. The presence of immature plasma cells characterized by high nucleus to cytoplasm ratio, visible nucleolus and presence of Mott cells and Russell bodies are independent poor prognostic factors. The clinician should differentiate PMMPE from secondary pleural effusion as it is associated with a significantly worse prognosis and poor overall survival.
format Online
Article
Text
id pubmed-4974434
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-49744342016-08-12 Primary malignant myelomatous pleural effusion Mangla, Ankit Agarwal, Nikki Kim, George J. Catchatourian, Rosalind Clin Case Rep Case Reports Primary malignant myelomatous pleural effusion (PMMPE) occurs in less than 1% of patients with multiple myeloma and is diagnosed either by visualization of plasma cells on cytology or by positive flow cytometry. The presence of immature plasma cells characterized by high nucleus to cytoplasm ratio, visible nucleolus and presence of Mott cells and Russell bodies are independent poor prognostic factors. The clinician should differentiate PMMPE from secondary pleural effusion as it is associated with a significantly worse prognosis and poor overall survival. John Wiley and Sons Inc. 2016-07-15 /pmc/articles/PMC4974434/ /pubmed/27525090 http://dx.doi.org/10.1002/ccr3.634 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Mangla, Ankit
Agarwal, Nikki
Kim, George J.
Catchatourian, Rosalind
Primary malignant myelomatous pleural effusion
title Primary malignant myelomatous pleural effusion
title_full Primary malignant myelomatous pleural effusion
title_fullStr Primary malignant myelomatous pleural effusion
title_full_unstemmed Primary malignant myelomatous pleural effusion
title_short Primary malignant myelomatous pleural effusion
title_sort primary malignant myelomatous pleural effusion
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974434/
https://www.ncbi.nlm.nih.gov/pubmed/27525090
http://dx.doi.org/10.1002/ccr3.634
work_keys_str_mv AT manglaankit primarymalignantmyelomatouspleuraleffusion
AT agarwalnikki primarymalignantmyelomatouspleuraleffusion
AT kimgeorgej primarymalignantmyelomatouspleuraleffusion
AT catchatourianrosalind primarymalignantmyelomatouspleuraleffusion

Ejemplares similares