ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

Lipid accumulation in macrophages has profound effects on macrophage gene expression and contributes to the development of atherosclerosis. Here, we report that angiopoietin-like protein 4 (ANGPTL4) is the most highly upregulated gene in foamy macrophages and it's absence in haematopoietic cell...

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Detalles Bibliográficos
Autores principales: Aryal, Binod, Rotllan, Noemi, Araldi, Elisa, Ramírez, Cristina M., He, Shun, Chousterman, Benjamin G., Fenn, Ashley M., Wanschel, Amarylis, Madrigal-Matute, Julio, Warrier, Nikhil, Martín-Ventura, Jose L., Swirski, Filip K., Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974469/
https://www.ncbi.nlm.nih.gov/pubmed/27460411
http://dx.doi.org/10.1038/ncomms12313

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