Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox. Ectromelia virus (ECTV) is naturally-occurring and responsible for severe mortal...

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Detalles Bibliográficos
Autores principales: Garver, Jennifer, Weber, Lauren, Vela, Eric M., Anderson, Mike, Warren, Richard, Merchlinsky, Michael, Houchens, Christopher, Rogers, James V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974538/
https://www.ncbi.nlm.nih.gov/pubmed/27455306
http://dx.doi.org/10.3390/v8070203

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