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HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system

The loss of gut epithelium integrity leads to translocation of microbes and microbial products resulting in immune activation and drives systemic inflammation in acquired immunodeficiency syndrome (AIDS) patients. Although viral loads in HIV patients are significantly reduced in the post-cART era, i...

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Detalles Bibliográficos
Autores principales:	Guedia, Joy, Brun, Paola, Bhave, Sukhada, Fitting, Sylvia, Kang, Minho, Dewey, William L., Hauser, Kurt F., Akbarali, Hamid I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974559/ https://www.ncbi.nlm.nih.gov/pubmed/27491828 http://dx.doi.org/10.1038/srep31203

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