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Loss of ADAMTS4 reduces high fat diet-induced atherosclerosis and enhances plaque stability in ApoE(−/−) mice

Atherosclerosis is a chronic inflammatory disease characterized by formation of lipid-rich plaques on the inner walls of arteries. ADAMTS4 (a disintegrin-like and metalloproteinase with thrombospondin motifs-4) is a secreted proteinase that regulates versican turnover in the arterial wall and athero...

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Detalles Bibliográficos
Autores principales:	Kumar, Saran, Chen, Mo, Li, Yan, Wong, Fiona H. S., Thiam, Chung Wee, Hossain, Md Zakir, Poh, Kian Keong, Hirohata, Satoshi, Ogawa, Hiroko, Angeli, Véronique, Ge, Ruowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974561/ https://www.ncbi.nlm.nih.gov/pubmed/27491335 http://dx.doi.org/10.1038/srep31130

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