Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants

Sepsis caused by Gram-positive bacterial pathogens is a major fatal disease but its molecular basis remains elusive. Toll-like receptor 2 (TLR2) has been implicated in the orchestration of inflammation and sepsis but its role appears to vary for different pathogen species and clones. Accordingly, St...

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Detalles Bibliográficos
Autores principales: Hanzelmann, Dennis, Joo, Hwang-Soo, Franz-Wachtel, Mirita, Hertlein, Tobias, Stevanovic, Stefan, Macek, Boris, Wolz, Christiane, Götz, Friedrich, Otto, Michael, Kretschmer, Dorothee, Peschel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974576/
https://www.ncbi.nlm.nih.gov/pubmed/27470911
http://dx.doi.org/10.1038/ncomms12304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974576/
https://www.ncbi.nlm.nih.gov/pubmed/27470911
http://dx.doi.org/10.1038/ncomms12304

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