Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs

The molecular mechanisms that regulate B-cell development and tolerance remain incompletely understood. In this study, we identify a critical role for the miR-17∼92 microRNA cluster in regulating B-cell central tolerance and demonstrate that these miRNAs control early B-cell development in a cell-in...

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Detalles Bibliográficos
Autores principales: Lai, Maoyi, Gonzalez-Martin, Alicia, Cooper, Anthony B., Oda, Hiroyo, Jin, Hyun Yong, Shepherd, Jovan, He, Linling, Zhu, Jiang, Nemazee, David, Xiao, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974641/
https://www.ncbi.nlm.nih.gov/pubmed/27481093
http://dx.doi.org/10.1038/ncomms12207

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