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Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells

Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly modulate cell proliferation and survival. Here, we engineered microscale progenitor cardiac spheres from human pluripotent stem cells a...

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Detalles Bibliográficos
Autores principales:	Jha, Rajneesh, Wu, Qingling, Singh, Monalisa, Preininger, Marcela K., Han, Pengcheng, Ding, Gouliang, Cho, Hee Cheol, Jo, Hanjoong, Maher, Kevin O., Wagner, Mary B., Xu, Chunhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974658/ https://www.ncbi.nlm.nih.gov/pubmed/27492371 http://dx.doi.org/10.1038/srep30956

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