The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth

Dysfunctions in ribosome biogenesis cause developmental defects and increased cancer susceptibility; however, the connection between ribosome assembly and tumorigenesis remains unestablished. Here we show that hCINAP (also named AK6) is required for human 18S rRNA processing and 40S subunit assembly...

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Detalles Bibliográficos
Autores principales: Bai, Dongmei, Zhang, Jinfang, Li, Tingting, Hang, Runlai, Liu, Yong, Tian, Yonglu, Huang, Dadu, Qu, Linglong, Cao, Xiaofeng, Ji, Jiafu, Zheng, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974663/
https://www.ncbi.nlm.nih.gov/pubmed/27477389
http://dx.doi.org/10.1038/ncomms12310

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