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Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study

BACKGROUND: This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20–40 years in a nationwide population database in Taiwan. METHODS: Subjects were selected from Taiwan’s National Health Insurance Research Database for the period 2001–2008 and were followed up...

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Autores principales: Leu, Tsai-Hsueh, Chang, Wei-Chun, Lin, Jeff Chien-Fu, Lo, Chi, Liang, Wen-Miin, Chang, Yu-Jun, Shih, Dann-Pyng, Wu, Cheng-Chun, Cheng, Chi-Fung, Wei, Sy-Jye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974740/
https://www.ncbi.nlm.nih.gov/pubmed/27496130
http://dx.doi.org/10.1186/s12891-016-1166-9
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author Leu, Tsai-Hsueh
Chang, Wei-Chun
Lin, Jeff Chien-Fu
Lo, Chi
Liang, Wen-Miin
Chang, Yu-Jun
Shih, Dann-Pyng
Wu, Cheng-Chun
Cheng, Chi-Fung
Wei, Sy-Jye
author_facet Leu, Tsai-Hsueh
Chang, Wei-Chun
Lin, Jeff Chien-Fu
Lo, Chi
Liang, Wen-Miin
Chang, Yu-Jun
Shih, Dann-Pyng
Wu, Cheng-Chun
Cheng, Chi-Fung
Wei, Sy-Jye
author_sort Leu, Tsai-Hsueh
collection PubMed
description BACKGROUND: This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20–40 years in a nationwide population database in Taiwan. METHODS: Subjects were selected from Taiwan’s National Health Insurance Research Database for the period 2001–2008 and were followed up until the end of 2010. A total of 4,523 subjects were admitted for the first time with primary diagnosis of hip fracture and treated with operation. RESULTS: The overall annual incidence, mortality, and standardized mortality ratio (SMR) decreased from 7.68 to 7.23 per 100,000, from 1.37 % to 0.94 %, and from 9.06 to 6.71, respectively, from 2001 to 2008. The 1-year, 2-year, 3-year, 5-year, and 10-year mortality rates were 1.28 %, 2.44 %, 3.54 %, 5.32 %, and 10.50 %, respectively for the whole cohort. The 1-year, 2-year, 3-year, 5-year, and 10-year SMRs were 8.33, 7.59, 7.28, 6.39, and 5.82, respectively, for the whole cohort. Risk factors for overall death were male gender, trochanteric fracture, hemiarthroplasty, and higher Charlson comorbidity index (CCI) scores. CONCLUSIONS: The high SMRs found in the present study suggest that young adults with former hip fracture should be closely followed up to prevent early mortality. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12891-016-1166-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-49747402016-08-06 Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study Leu, Tsai-Hsueh Chang, Wei-Chun Lin, Jeff Chien-Fu Lo, Chi Liang, Wen-Miin Chang, Yu-Jun Shih, Dann-Pyng Wu, Cheng-Chun Cheng, Chi-Fung Wei, Sy-Jye BMC Musculoskelet Disord Research Article BACKGROUND: This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20–40 years in a nationwide population database in Taiwan. METHODS: Subjects were selected from Taiwan’s National Health Insurance Research Database for the period 2001–2008 and were followed up until the end of 2010. A total of 4,523 subjects were admitted for the first time with primary diagnosis of hip fracture and treated with operation. RESULTS: The overall annual incidence, mortality, and standardized mortality ratio (SMR) decreased from 7.68 to 7.23 per 100,000, from 1.37 % to 0.94 %, and from 9.06 to 6.71, respectively, from 2001 to 2008. The 1-year, 2-year, 3-year, 5-year, and 10-year mortality rates were 1.28 %, 2.44 %, 3.54 %, 5.32 %, and 10.50 %, respectively for the whole cohort. The 1-year, 2-year, 3-year, 5-year, and 10-year SMRs were 8.33, 7.59, 7.28, 6.39, and 5.82, respectively, for the whole cohort. Risk factors for overall death were male gender, trochanteric fracture, hemiarthroplasty, and higher Charlson comorbidity index (CCI) scores. CONCLUSIONS: The high SMRs found in the present study suggest that young adults with former hip fracture should be closely followed up to prevent early mortality. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12891-016-1166-9) contains supplementary material, which is available to authorized users. BioMed Central 2016-08-05 /pmc/articles/PMC4974740/ /pubmed/27496130 http://dx.doi.org/10.1186/s12891-016-1166-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Leu, Tsai-Hsueh
Chang, Wei-Chun
Lin, Jeff Chien-Fu
Lo, Chi
Liang, Wen-Miin
Chang, Yu-Jun
Shih, Dann-Pyng
Wu, Cheng-Chun
Cheng, Chi-Fung
Wei, Sy-Jye
Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
title Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
title_full Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
title_fullStr Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
title_full_unstemmed Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
title_short Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
title_sort incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974740/
https://www.ncbi.nlm.nih.gov/pubmed/27496130
http://dx.doi.org/10.1186/s12891-016-1166-9
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