Open questions: what about the ‘other’ Rho GTPases?

Rho GTPases have many and diverse roles in cell physiology, and some family members are very well studied, including RhoA, Rac1 and Cdc42. But many are relatively neglected, and fundamental questions about their mechanisms and functions remain open.

Detalles Bibliográficos
Autor principal: Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974793/
https://www.ncbi.nlm.nih.gov/pubmed/27491358
http://dx.doi.org/10.1186/s12915-016-0289-7
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author Ridley, Anne J.
author_facet Ridley, Anne J.
author_sort Ridley, Anne J.
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description Rho GTPases have many and diverse roles in cell physiology, and some family members are very well studied, including RhoA, Rac1 and Cdc42. But many are relatively neglected, and fundamental questions about their mechanisms and functions remain open.
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spelling pubmed-49747932016-08-06 Open questions: what about the ‘other’ Rho GTPases? Ridley, Anne J. BMC Biol Comment Rho GTPases have many and diverse roles in cell physiology, and some family members are very well studied, including RhoA, Rac1 and Cdc42. But many are relatively neglected, and fundamental questions about their mechanisms and functions remain open. BioMed Central 2016-08-04 /pmc/articles/PMC4974793/ /pubmed/27491358 http://dx.doi.org/10.1186/s12915-016-0289-7 Text en © Ridley. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Ridley, Anne J.
Open questions: what about the ‘other’ Rho GTPases?
title Open questions: what about the ‘other’ Rho GTPases?
title_full Open questions: what about the ‘other’ Rho GTPases?
title_fullStr Open questions: what about the ‘other’ Rho GTPases?
title_full_unstemmed Open questions: what about the ‘other’ Rho GTPases?
title_short Open questions: what about the ‘other’ Rho GTPases?
title_sort open questions: what about the ‘other’ rho gtpases?
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974793/
https://www.ncbi.nlm.nih.gov/pubmed/27491358
http://dx.doi.org/10.1186/s12915-016-0289-7
work_keys_str_mv AT ridleyannej openquestionswhatabouttheotherrhogtpases

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