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S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells

BACKGROUND: The S6 Kinase (S6K) proteins are some of the main downstream effectors of the mammalian Target Of Rapamycin (mTOR) and act as key regulators of protein synthesis and cell growth. S6K is overexpressed in a variety of human tumors and is correlated to poor prognosis in prostate cancer. Due...

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Detalles Bibliográficos
Autores principales:	Amaral, Camila L., Freitas, Lidia B., Tamura, Rodrigo E., Tavares, Mariana R., Pavan, Isadora C. B., Bajgelman, Marcio C., Simabuco, Fernando M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974797/ https://www.ncbi.nlm.nih.gov/pubmed/27491285 http://dx.doi.org/10.1186/s12885-016-2629-y

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