Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies

OBJECTIVE: We investigated the association between 52 risk variants identified through genome-wide association studies and disease severity in multiple sclerosis (MS). METHODS: Ten unique MS case data sets were analyzed. The Multiple Sclerosis Severity Score (MSSS) was calculated using the Expanded...

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Detalles Bibliográficos
Autores principales: George, Michaela F., Briggs, Farren B.S., Shao, Xiaorong, Gianfrancesco, Milena A., Kockum, Ingrid, Harbo, Hanne F., Celius, Elisabeth G., Bos, Steffan D., Hedström, Anna, Shen, Ling, Bernstein, Allan, Alfredsson, Lars, Hillert, Jan, Olsson, Tomas, Patsopoulos, Nikolaos A., De Jager, Philip L., Oturai, Annette B., Søndergaard, Helle B., Sellebjerg, Finn, Sorensen, Per S., Gomez, Refujia, Caillier, Stacy J., Cree, Bruce A.C., Oksenberg, Jorge R., Hauser, Stephen L., D'Alfonso, Sandra, Leone, Maurizio A., Boneschi, Filippo Martinelli, Sorosina, Melissa, van der Mei, Ingrid, Taylor, Bruce V., Zhou, Yuan, Schaefer, Catherine, Barcellos, Lisa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974846/
https://www.ncbi.nlm.nih.gov/pubmed/27540591
http://dx.doi.org/10.1212/NXG.0000000000000087

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