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Deep brain stimulation for the treatment of uncommon tremor syndromes
Introduction: Deep brain stimulation (DBS) has become a standard therapy for the treatment of select cases of medication refractory essential tremor and Parkinson’s disease however the effectiveness and long-term outcomes of DBS in other uncommon and complex tremor syndromes has not been well establ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975099/ https://www.ncbi.nlm.nih.gov/pubmed/27228280 http://dx.doi.org/10.1080/14737175.2016.1194756 |
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author | Ramirez-Zamora, Adolfo Okun, Michael S. |
author_facet | Ramirez-Zamora, Adolfo Okun, Michael S. |
author_sort | Ramirez-Zamora, Adolfo |
collection | PubMed |
description | Introduction: Deep brain stimulation (DBS) has become a standard therapy for the treatment of select cases of medication refractory essential tremor and Parkinson’s disease however the effectiveness and long-term outcomes of DBS in other uncommon and complex tremor syndromes has not been well established. Traditionally, the ventralis intermedius nucleus (VIM) of the thalamus has been considered the main target for medically intractable tremors; however alternative brain regions and improvements in stereotactic techniques and hardware may soon change the horizon for treatment of complex tremors. Areas covered: In this article, we conducted a PubMed search using different combinations between the terms ‘Uncommon tremors’, ‘Dystonic tremor’, ‘Holmes tremor’ ‘Midbrain tremor’, ‘Rubral tremor’, ‘Cerebellar tremor’, ‘outflow tremor’, ‘Multiple Sclerosis tremor’, ‘Post-traumatic tremor’, ‘Neuropathic tremor’, and ‘Deep Brain Stimulation/DBS’. Additionally, we examined and summarized the current state of evolving interventions for treatment of complex tremor syndromes. Expert c ommentary: Recently reported interventions for rare tremors include stimulation of the posterior subthalamic area, globus pallidus internus, ventralis oralis anterior/posterior thalamic subnuclei, and the use of dual lead stimulation in one or more of these targets. Treatment should be individualized and dictated by tremor phenomenology and associated clinical features. |
format | Online Article Text |
id | pubmed-4975099 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-49750992016-08-25 Deep brain stimulation for the treatment of uncommon tremor syndromes Ramirez-Zamora, Adolfo Okun, Michael S. Expert Rev Neurother Review Introduction: Deep brain stimulation (DBS) has become a standard therapy for the treatment of select cases of medication refractory essential tremor and Parkinson’s disease however the effectiveness and long-term outcomes of DBS in other uncommon and complex tremor syndromes has not been well established. Traditionally, the ventralis intermedius nucleus (VIM) of the thalamus has been considered the main target for medically intractable tremors; however alternative brain regions and improvements in stereotactic techniques and hardware may soon change the horizon for treatment of complex tremors. Areas covered: In this article, we conducted a PubMed search using different combinations between the terms ‘Uncommon tremors’, ‘Dystonic tremor’, ‘Holmes tremor’ ‘Midbrain tremor’, ‘Rubral tremor’, ‘Cerebellar tremor’, ‘outflow tremor’, ‘Multiple Sclerosis tremor’, ‘Post-traumatic tremor’, ‘Neuropathic tremor’, and ‘Deep Brain Stimulation/DBS’. Additionally, we examined and summarized the current state of evolving interventions for treatment of complex tremor syndromes. Expert c ommentary: Recently reported interventions for rare tremors include stimulation of the posterior subthalamic area, globus pallidus internus, ventralis oralis anterior/posterior thalamic subnuclei, and the use of dual lead stimulation in one or more of these targets. Treatment should be individualized and dictated by tremor phenomenology and associated clinical features. Taylor & Francis 2016-08-02 2016-06-09 /pmc/articles/PMC4975099/ /pubmed/27228280 http://dx.doi.org/10.1080/14737175.2016.1194756 Text en © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
spellingShingle | Review Ramirez-Zamora, Adolfo Okun, Michael S. Deep brain stimulation for the treatment of uncommon tremor syndromes |
title | Deep brain stimulation for the treatment of uncommon tremor syndromes |
title_full | Deep brain stimulation for the treatment of uncommon tremor syndromes |
title_fullStr | Deep brain stimulation for the treatment of uncommon tremor syndromes |
title_full_unstemmed | Deep brain stimulation for the treatment of uncommon tremor syndromes |
title_short | Deep brain stimulation for the treatment of uncommon tremor syndromes |
title_sort | deep brain stimulation for the treatment of uncommon tremor syndromes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975099/ https://www.ncbi.nlm.nih.gov/pubmed/27228280 http://dx.doi.org/10.1080/14737175.2016.1194756 |
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