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Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers

Among the most prevalent neoplasias, breast cancer shows an astonishing tendency. Unfortunately this cancer has a high mortality worldwide, requiring sustained management of all actors involved in public health in order to get an early diagnosis and treatment. The methods associated with conventiona...

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Detalles Bibliográficos
Autores principales: Tovar, Cristian Layton, Zerón, Hugo Mendieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975167/
https://www.ncbi.nlm.nih.gov/pubmed/27683438
http://dx.doi.org/10.1371/journal.pone.0012860.
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author Tovar, Cristian Layton
Zerón, Hugo Mendieta
author_facet Tovar, Cristian Layton
Zerón, Hugo Mendieta
author_sort Tovar, Cristian Layton
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description Among the most prevalent neoplasias, breast cancer shows an astonishing tendency. Unfortunately this cancer has a high mortality worldwide, requiring sustained management of all actors involved in public health in order to get an early diagnosis and treatment. The methods associated with conventional cytogenetics and molecular cell culture, besides early detection of gene expression patterns associated with cancer susceptibility, have contributed to identify inherited genes and metabolic disorders related to obesity, which are also involved in breast cancer. In any case, a broad study of the above mentioned factors can give a predictive value to support the design of public health models to determine cancer risk in order to decrease the mortality from this disease. (1) Cell cultures offers a wide range of scientific approach for the study of breast cancer, including the analysis of biological function of several compounds in search of increasingly effective treatments with fewer side effects against this malignancy. (2)
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spelling pubmed-49751672016-09-28 Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers Tovar, Cristian Layton Zerón, Hugo Mendieta EJIFCC Research Article Among the most prevalent neoplasias, breast cancer shows an astonishing tendency. Unfortunately this cancer has a high mortality worldwide, requiring sustained management of all actors involved in public health in order to get an early diagnosis and treatment. The methods associated with conventional cytogenetics and molecular cell culture, besides early detection of gene expression patterns associated with cancer susceptibility, have contributed to identify inherited genes and metabolic disorders related to obesity, which are also involved in breast cancer. In any case, a broad study of the above mentioned factors can give a predictive value to support the design of public health models to determine cancer risk in order to decrease the mortality from this disease. (1) Cell cultures offers a wide range of scientific approach for the study of breast cancer, including the analysis of biological function of several compounds in search of increasingly effective treatments with fewer side effects against this malignancy. (2) The Communications and Publications Division (CPD) of the IFCC 2013-07-16 /pmc/articles/PMC4975167/ /pubmed/27683438 http://dx.doi.org/10.1371/journal.pone.0012860. Text en Copyright © 2015 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tovar, Cristian Layton
Zerón, Hugo Mendieta
Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers
title Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers
title_full Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers
title_fullStr Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers
title_full_unstemmed Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers
title_short Cell Culture Models and Pharmacological Perspective for the Study of Breast Cancer Markers
title_sort cell culture models and pharmacological perspective for the study of breast cancer markers
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975167/
https://www.ncbi.nlm.nih.gov/pubmed/27683438
http://dx.doi.org/10.1371/journal.pone.0012860.
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