Hepcidin and Its Role in Iron Homeostasis

Hepcidin, a small peptide secreted mainly by the liver, plays a central role in iron status regulation. The experiments on hepcidin seemed very promising and gave new life to understanding iron metabolism. Many authors suggest that hepcidin measurement can be used as a clinical tool for the diagnosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwapisz, Justyna, Slomka, Artur, Zekanowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975279/
https://www.ncbi.nlm.nih.gov/pubmed/27683336
_version_ 1782446695732215808
author Kwapisz, Justyna
Slomka, Artur
Zekanowska, Ewa
author_facet Kwapisz, Justyna
Slomka, Artur
Zekanowska, Ewa
author_sort Kwapisz, Justyna
collection PubMed
description Hepcidin, a small peptide secreted mainly by the liver, plays a central role in iron status regulation. The experiments on hepcidin seemed very promising and gave new life to understanding iron metabolism. Many authors suggest that hepcidin measurement can be used as a clinical tool for the diagnosis and management of a wide range of iron-related disorders. The current review presents data concerning hepcidin, especially its biology, mechanism of action and its role in pathomechanism of many diseases.
format Online
Article
Text
id pubmed-4975279
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher The Communications and Publications Division (CPD) of the IFCC
record_format MEDLINE/PubMed
spelling pubmed-49752792016-09-28 Hepcidin and Its Role in Iron Homeostasis Kwapisz, Justyna Slomka, Artur Zekanowska, Ewa EJIFCC Research Article Hepcidin, a small peptide secreted mainly by the liver, plays a central role in iron status regulation. The experiments on hepcidin seemed very promising and gave new life to understanding iron metabolism. Many authors suggest that hepcidin measurement can be used as a clinical tool for the diagnosis and management of a wide range of iron-related disorders. The current review presents data concerning hepcidin, especially its biology, mechanism of action and its role in pathomechanism of many diseases. The Communications and Publications Division (CPD) of the IFCC 2009-08-25 /pmc/articles/PMC4975279/ /pubmed/27683336 Text en Copyright © 2009 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kwapisz, Justyna
Slomka, Artur
Zekanowska, Ewa
Hepcidin and Its Role in Iron Homeostasis
title Hepcidin and Its Role in Iron Homeostasis
title_full Hepcidin and Its Role in Iron Homeostasis
title_fullStr Hepcidin and Its Role in Iron Homeostasis
title_full_unstemmed Hepcidin and Its Role in Iron Homeostasis
title_short Hepcidin and Its Role in Iron Homeostasis
title_sort hepcidin and its role in iron homeostasis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975279/
https://www.ncbi.nlm.nih.gov/pubmed/27683336
work_keys_str_mv AT kwapiszjustyna hepcidinanditsroleinironhomeostasis
AT slomkaartur hepcidinanditsroleinironhomeostasis
AT zekanowskaewa hepcidinanditsroleinironhomeostasis

Ejemplares similares