The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis

Interleukin-33 (IL-33) is a newly found cytokine of the interleukin-1 (IL-1) family. It’s mainly expressed by epithelial and endothelial cells. This expression is upregulated by pro-inflammatory stimulation, thus has an important role in inflammatory responses, such as hypersensitive diseases (asthm...

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Detalles Bibliográficos
Autores principales: Fulgheri, Gabriele, Malinowski, Bartosz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975324/
https://www.ncbi.nlm.nih.gov/pubmed/27683395
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author Fulgheri, Gabriele
Malinowski, Bartosz
author_facet Fulgheri, Gabriele
Malinowski, Bartosz
author_sort Fulgheri, Gabriele
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description Interleukin-33 (IL-33) is a newly found cytokine of the interleukin-1 (IL-1) family. It’s mainly expressed by epithelial and endothelial cells. This expression is upregulated by pro-inflammatory stimulation, thus has an important role in inflammatory responses, such as hypersensitive diseases (asthma), autoimmune diseases (rheumatoid arthritis), cardiovascular diseases (heart failure) and neurodegenerative diseases (Alzheimer). Several studies explored the complicated mechanism of IL-33 action in asthma and atherosclerosis, as this IL is significantly increased in these pathologies, and suggested its potential use in the therapeutic procedures.
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spelling pubmed-49753242016-09-28 The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis Fulgheri, Gabriele Malinowski, Bartosz EJIFCC Research Article Interleukin-33 (IL-33) is a newly found cytokine of the interleukin-1 (IL-1) family. It’s mainly expressed by epithelial and endothelial cells. This expression is upregulated by pro-inflammatory stimulation, thus has an important role in inflammatory responses, such as hypersensitive diseases (asthma), autoimmune diseases (rheumatoid arthritis), cardiovascular diseases (heart failure) and neurodegenerative diseases (Alzheimer). Several studies explored the complicated mechanism of IL-33 action in asthma and atherosclerosis, as this IL is significantly increased in these pathologies, and suggested its potential use in the therapeutic procedures. The Communications and Publications Division (CPD) of the IFCC 2011-10-05 /pmc/articles/PMC4975324/ /pubmed/27683395 Text en Copyright © 2011 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Fulgheri, Gabriele
Malinowski, Bartosz
The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
title The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
title_full The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
title_fullStr The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
title_full_unstemmed The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
title_short The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
title_sort role of il-33 in the inflammation process of asthma and atherosclerosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975324/
https://www.ncbi.nlm.nih.gov/pubmed/27683395
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