Cargando…
The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis
Interleukin-33 (IL-33) is a newly found cytokine of the interleukin-1 (IL-1) family. It’s mainly expressed by epithelial and endothelial cells. This expression is upregulated by pro-inflammatory stimulation, thus has an important role in inflammatory responses, such as hypersensitive diseases (asthm...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Communications and Publications Division (CPD) of the IFCC
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975324/ https://www.ncbi.nlm.nih.gov/pubmed/27683395 |
_version_ | 1782446705742970880 |
---|---|
author | Fulgheri, Gabriele Malinowski, Bartosz |
author_facet | Fulgheri, Gabriele Malinowski, Bartosz |
author_sort | Fulgheri, Gabriele |
collection | PubMed |
description | Interleukin-33 (IL-33) is a newly found cytokine of the interleukin-1 (IL-1) family. It’s mainly expressed by epithelial and endothelial cells. This expression is upregulated by pro-inflammatory stimulation, thus has an important role in inflammatory responses, such as hypersensitive diseases (asthma), autoimmune diseases (rheumatoid arthritis), cardiovascular diseases (heart failure) and neurodegenerative diseases (Alzheimer). Several studies explored the complicated mechanism of IL-33 action in asthma and atherosclerosis, as this IL is significantly increased in these pathologies, and suggested its potential use in the therapeutic procedures. |
format | Online Article Text |
id | pubmed-4975324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Communications and Publications Division (CPD) of the IFCC |
record_format | MEDLINE/PubMed |
spelling | pubmed-49753242016-09-28 The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis Fulgheri, Gabriele Malinowski, Bartosz EJIFCC Research Article Interleukin-33 (IL-33) is a newly found cytokine of the interleukin-1 (IL-1) family. It’s mainly expressed by epithelial and endothelial cells. This expression is upregulated by pro-inflammatory stimulation, thus has an important role in inflammatory responses, such as hypersensitive diseases (asthma), autoimmune diseases (rheumatoid arthritis), cardiovascular diseases (heart failure) and neurodegenerative diseases (Alzheimer). Several studies explored the complicated mechanism of IL-33 action in asthma and atherosclerosis, as this IL is significantly increased in these pathologies, and suggested its potential use in the therapeutic procedures. The Communications and Publications Division (CPD) of the IFCC 2011-10-05 /pmc/articles/PMC4975324/ /pubmed/27683395 Text en Copyright © 2011 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Fulgheri, Gabriele Malinowski, Bartosz The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis |
title | The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis |
title_full | The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis |
title_fullStr | The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis |
title_full_unstemmed | The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis |
title_short | The Role of IL-33 in the Inflammation Process of Asthma and Atherosclerosis |
title_sort | role of il-33 in the inflammation process of asthma and atherosclerosis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975324/ https://www.ncbi.nlm.nih.gov/pubmed/27683395 |
work_keys_str_mv | AT fulgherigabriele theroleofil33intheinflammationprocessofasthmaandatherosclerosis AT malinowskibartosz theroleofil33intheinflammationprocessofasthmaandatherosclerosis AT fulgherigabriele roleofil33intheinflammationprocessofasthmaandatherosclerosis AT malinowskibartosz roleofil33intheinflammationprocessofasthmaandatherosclerosis |