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Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia
Pain is a hallmark feature of sickle cell anemia (SCA) but management of chronic as well as acute pain remains a major challenge. Mouse models of SCA are essential to examine the mechanisms of pain and develop novel therapeutics. To facilitate this effort, we compared humanized homozygous BERK and T...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975462/ https://www.ncbi.nlm.nih.gov/pubmed/27494522 http://dx.doi.org/10.1371/journal.pone.0160608 |