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Modified AS1411 Aptamer Suppresses Hepatocellular Carcinoma by Up-Regulating Galectin-14

Aptamers are small synthetic oligonucleotides that bind to target proteins with high specificity and affinity. AS1411 is an aptamer that binds to nucleolin, which is overexpressed in the cytoplasm and occurs on the surface of cancer cells. We investigated the therapeutic potential of aptamers in hep...

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Detalles Bibliográficos
Autores principales:	Cho, Yuri, Lee, Yun Bin, Lee, Jeong-Hoon, Lee, Dong Hyeon, Cho, Eun Ju, Yu, Su Jong, Kim, Yoon Jun, Kim, Jong In, Im, Jong Hun, Lee, Jung Hwan, Oh, Eun Ju, Yoon, Jung-Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975508/ https://www.ncbi.nlm.nih.gov/pubmed/27494117 http://dx.doi.org/10.1371/journal.pone.0160822

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