Subclass analysis of donor HLA‐specific IgG in antibody‐incompatible renal transplantation reveals a significant association of IgG(4) with rejection and graft failure

Donor HLA‐specific antibodies (DSAs) can cause rejection and graft loss after renal transplantation, but their levels measured by the current assays are not fully predictive of outcomes. We investigated whether IgG subclasses of DSA were associated with early rejection and graft failure. DSA levels...

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Detalles Bibliográficos
Autores principales: Khovanova, Natasha, Daga, Sunil, Shaikhina, Torgyn, Krishnan, Nithya, Jones, James, Zehnder, Daniel, Mitchell, Daniel, Higgins, Robert, Briggs, David, Lowe, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975692/
https://www.ncbi.nlm.nih.gov/pubmed/26264744
http://dx.doi.org/10.1111/tri.12648

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