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Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature
Escherichia vulneris is an opportunistic human pathogen. It has been primarily reported in adult patients and invasive infections have been observed in immune-suppressed individuals. This is the first report of E. vulneris causing complicated diarrhoea and sepsis in an infant. Two month old sick inf...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975714/ https://www.ncbi.nlm.nih.gov/pubmed/27536376 http://dx.doi.org/10.1016/j.nmni.2016.07.002 |
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author | Jain, S. Nagarjuna, D. Gaind, R. Chopra, S. Debata, P.K. Dawar, R. Sardana, R. Yadav, M. |
author_facet | Jain, S. Nagarjuna, D. Gaind, R. Chopra, S. Debata, P.K. Dawar, R. Sardana, R. Yadav, M. |
author_sort | Jain, S. |
collection | PubMed |
description | Escherichia vulneris is an opportunistic human pathogen. It has been primarily reported in adult patients and invasive infections have been observed in immune-suppressed individuals. This is the first report of E. vulneris causing complicated diarrhoea and sepsis in an infant. Two month old sick infant, born full-term, was admitted to the paediatrics department with loose motions and refusal to feed for four days. E. vulneris was isolated from blood in pure culture. The isolate was characterized for diarrhoeal virulence markers: heat labile and heat stable toxins (LT, ST) and hemolysin (hlyA) by PCR. The presence of LT enterotoxin and hemolysin provides strong evidence of the diarrhoeagenic potential of E. vulneris, further leading to the invasive infection triggering sepsis. As E. vulneris can lead to serious complications, an attempt should be made in clinical laboratories to identify and further characterize this new Escherichia species. |
format | Online Article Text |
id | pubmed-4975714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49757142016-08-17 Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature Jain, S. Nagarjuna, D. Gaind, R. Chopra, S. Debata, P.K. Dawar, R. Sardana, R. Yadav, M. New Microbes New Infect Case Report Escherichia vulneris is an opportunistic human pathogen. It has been primarily reported in adult patients and invasive infections have been observed in immune-suppressed individuals. This is the first report of E. vulneris causing complicated diarrhoea and sepsis in an infant. Two month old sick infant, born full-term, was admitted to the paediatrics department with loose motions and refusal to feed for four days. E. vulneris was isolated from blood in pure culture. The isolate was characterized for diarrhoeal virulence markers: heat labile and heat stable toxins (LT, ST) and hemolysin (hlyA) by PCR. The presence of LT enterotoxin and hemolysin provides strong evidence of the diarrhoeagenic potential of E. vulneris, further leading to the invasive infection triggering sepsis. As E. vulneris can lead to serious complications, an attempt should be made in clinical laboratories to identify and further characterize this new Escherichia species. Elsevier 2016-07-09 /pmc/articles/PMC4975714/ /pubmed/27536376 http://dx.doi.org/10.1016/j.nmni.2016.07.002 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Jain, S. Nagarjuna, D. Gaind, R. Chopra, S. Debata, P.K. Dawar, R. Sardana, R. Yadav, M. Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature |
title | Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature |
title_full | Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature |
title_fullStr | Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature |
title_full_unstemmed | Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature |
title_short | Escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. A case report and review of literature |
title_sort | escherichia vulneris: an unusual cause of complicated diarrhoea and sepsis in an infant. a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975714/ https://www.ncbi.nlm.nih.gov/pubmed/27536376 http://dx.doi.org/10.1016/j.nmni.2016.07.002 |
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