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Mass spectrometric determination of early and advanced glycation in biology

Protein glycation in biological systems occurs predominantly on lysine, arginine and N-terminal residues of proteins. Major quantitative glycation adducts are found at mean extents of modification of 1–5 mol percent of proteins. These are glucose-derived fructosamine on lysine and N-terminal residue...

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Detalles Bibliográficos
Autores principales: Rabbani, Naila, Ashour, Amal, Thornalley, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975772/
https://www.ncbi.nlm.nih.gov/pubmed/27438287
http://dx.doi.org/10.1007/s10719-016-9709-8