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T-cell abnormalities in common variable immunodeficiency: the hidden defect
This review discusses how the T-cell compartment in common variable immunodeficiency is marked by the premature arrest in thymic output, leading to T-cell exhaustion and immune dysregulation. Although B cells have been the main focus of the disorder, ample experimental data suggest that T-cell abnor...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975840/ https://www.ncbi.nlm.nih.gov/pubmed/27153873 http://dx.doi.org/10.1136/jclinpath-2015-203351 |