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Recombinant production of medium- to large-sized peptides in Escherichia coli using a cleavable self-aggregating tag
BACKGROUND: Peptides have recently become attractive for therapeutic applications. However, efficient production of medium- to large-sized peptides (30–100 amino acids [aa]) remains challenging both by recombinant and chemical synthesis. We previously reported the formation of active enzyme aggregat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975908/ https://www.ncbi.nlm.nih.gov/pubmed/27495238 http://dx.doi.org/10.1186/s12934-016-0534-3 |