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Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs
Acquired resistance to cancer drug therapies almost always occurs in advanced-stage patients even following a significant response to treatment. In addition to mutational mechanisms, various non-mutational resistance mechanisms have now been recognized. We previously described a chromatin-mediated s...
Autores principales: | Sahu, Nisebita, Stephan, Jean-Philippe, Cruz, Darlene Dela, Merchant, Mark, Haley, Benjamin, Bourgon, Richard, Classon, Marie, Settleman, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976141/ https://www.ncbi.nlm.nih.gov/pubmed/27484502 http://dx.doi.org/10.1038/ncomms12351 |
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