Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions

All cellular functions depend on the concerted action of multiple proteins organized in complex networks. To understand how selection acts on protein networks, we used the yeast mating receptor Ste2, a pheromone-activated G protein-coupled receptor, as a model system. In Saccharomyces cerevisiae, St...

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Detalles Bibliográficos
Autores principales: Di Roberto, Raphaël B., Chang, Belinda, Trusina, Ala, Peisajovich, Sergio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976203/
https://www.ncbi.nlm.nih.gov/pubmed/27487915
http://dx.doi.org/10.1038/ncomms12344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976203/
https://www.ncbi.nlm.nih.gov/pubmed/27487915
http://dx.doi.org/10.1038/ncomms12344

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