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Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells

Coordinated polarization of epithelial cells is a key step during morphogenesis that leads to the formation of an apical lumen. Rab11 and its interacting protein FIP5 are necessary for the targeting of apical endosomes to the midbody and apical membrane initiation site (AMIS) during lumenogenesis. H...

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Detalles Bibliográficos
Autores principales: Mangan, Anthony J., Sietsema, Daniel V., Li, Dongying, Moore, Jeffrey K., Citi, Sandra, Prekeris, Rytis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976216/
https://www.ncbi.nlm.nih.gov/pubmed/27484926
http://dx.doi.org/10.1038/ncomms12426