Cargando…

DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

Methylation at 5-cytosine (5-mC) is a fundamental epigenetic DNA modification associated recently with cardiac disease. In contrast, the role of 5-hydroxymethylcytosine (5-hmC)—5-mC's oxidation product—in cardiac biology and disease is unknown. Here we assess the hydroxymethylome in embryonic,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Greco, Carolina M., Kunderfranco, Paolo, Rubino, Marcello, Larcher, Veronica, Carullo, Pierluigi, Anselmo, Achille, Kurz, Kerstin, Carell, Thomas, Angius, Andrea, Latronico, Michael V. G., Papait, Roberto, Condorelli, Gianluigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976219/ https://www.ncbi.nlm.nih.gov/pubmed/27489048 http://dx.doi.org/10.1038/ncomms12418

Ejemplares similares

Epigenetics: a new mechanism of regulation of heart failure?
por: Papait, Roberto, et al.
Publicado: (2013)

Long Noncoding RNA: a New Player of Heart Failure?
por: Papait, Roberto, et al.
Publicado: (2013)

Dietary essential amino acids for the treatment of heart failure with reduced ejection fraction
por: Ragni, Maurizio, et al.
Publicado: (2023)

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer
por: Rubino, Marcello, et al.
Publicado: (2017)

Growth hormone-releasing hormone attenuates cardiac hypertrophy and improves heart function in pressure overload-induced heart failure
por: Gesmundo, Iacopo, et al.
Publicado: (2017)

Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation
por: Rizzi, R, et al.
Publicado: (2012)

T cell costimulation blockade blunts pressure overload-induced heart failure
por: Kallikourdis, Marinos, et al.
Publicado: (2017)

5‐Hydroxymethyl‐, 5‐Formyl‐ and 5‐Carboxydeoxycytidines as Oxidative Lesions and Epigenetic Marks
por: Schelter, Florian, et al.
Publicado: (2021)

Divergent Transcription of the Nkx2-5 Locus Generates Two Enhancer RNAs with Opposing Functions
por: Salamon, Irene, et al.
Publicado: (2020)

Role of Histone Demethylases in Cardiomyocytes Induced to Hypertrophy
por: Rosales, Wendy, et al.
Publicado: (2016)

Lycopene Inhibits Urotensin-II-Induced Cardiomyocyte Hypertrophy in Neonatal Rat Cardiomyocytes
por: Chao, Hung-Hsing, et al.
Publicado: (2014)

Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy
por: Kooij, Viola, et al.
Publicado: (2016)

DNA hydroxymethylation is associated with disease severity and persists at enhancers of oncogenic regions in multiple myeloma
por: Alberge, Jean-Baptiste, et al.
Publicado: (2020)

Marinobufagenin, Left Ventricular Hypertrophy and Residual Renal Function in Kidney Transplant Recipients
por: Bolignano, Davide, et al.
Publicado: (2023)

Pioglitazone Induces Cardiomyocyte Apoptosis and Inhibits Cardiomyocyte Hypertrophy Via VEGFR-2 Signaling Pathway
por: Zhong, Wenliang, et al.
Publicado: (2018)

Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo
por: Clerk, Angela, et al.
Publicado: (2022)

Age-Dependent Levels of 5-Methyl-, 5-Hydroxymethyl-, and 5-Formylcytosine in Human and Mouse Brain Tissues**
por: Wagner, Mirko, et al.
Publicado: (2015)

N-(Hydroxymethyl)ibogaine
por: Jarraya, Raoudha Mezghani, et al.
Publicado: (2008)

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy
por: Salvarani, Nicolò, et al.
Publicado: (2019)

NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy
por: Guo, Ningning, et al.
Publicado: (2021)

Regulation of myoglobin in hypertrophied rat cardiomyocytes in experimental pulmonary hypertension
por: Peters, E. L., et al.
Publicado: (2016)

Modeling Human Cardiac Hypertrophy in Stem Cell-Derived Cardiomyocytes
por: Ovchinnikova, Ekaterina, et al.
Publicado: (2018)

Luteolin suppresses lipopolysaccharide-induced cardiomyocyte hypertrophy and autophagy in vitro
por: Li, Xing, et al.
Publicado: (2019)

Effect of SKF-96365 on cardiomyocyte hypertrophy induced by angiotensin II
por: Cheng, Huijun, et al.
Publicado: (2020)

Herpud1 suppress angiotensin II induced hypertrophy in cardiomyocytes
por: Mikawa, Mei, et al.
Publicado: (2022)

T Cell Costimulation Blockade Blunts Age-Related Heart Failure
por: Martini, Elisa, et al.
Publicado: (2020)

Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy
por: Fernández, Carolina, et al.
Publicado: (2021)

Hydroxymethylation and tumors: can 5-hydroxymethylation be used as a marker for tumor diagnosis and treatment?
por: Xu, Tianmin, et al.
Publicado: (2020)

Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats
por: JIANG, F.L., et al.
Publicado: (2013)

Effect of ligustilide on Ang II-induced hypertrophy in cardiomyocytes and the potential mechanisms
por: LU, QUN, et al.
Publicado: (2014)

Effect of hepatocyte growth factor and angiotensin II on rat cardiomyocyte hypertrophy
por: Chen, Ai-Lan, et al.
Publicado: (2012)

Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation
por: Aguiar, Carla J, et al.
Publicado: (2014)

SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy
por: Li, Zhenzhen, et al.
Publicado: (2019)

The role of angiopoietin-like protein 4 in phenylephrine-induced cardiomyocyte hypertrophy
por: Sun, Yu, et al.
Publicado: (2019)

Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice
por: Alharbi, Hajed O., et al.
Publicado: (2022)

Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes
por: Fischer, Maximillian, et al.
Publicado: (2023)

Hydroxymethylation of DNA: an epigenetic marker
por: Richa, Rajneesh, et al.
Publicado: (2014)

Hydroxymethylated cytosine in development and disease
por: Pfeifer, Gerd P
Publicado: (2013)

DNA methylation/hydroxymethylation in melanoma
por: Fu, Siqi, et al.
Publicado: (2017)

Reductive Hydroxymethylation of 4‐Heteroarylpyridines
por: Hepburn, Hamish B., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mq32g1e63cesc0j44qckrvepn1