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Establishment of a tamoxifen-inducible Cre-driver mouse strain for widespread and temporal genetic modification in adult mice

Temporal genetic modification of mice using the ligand-inducible Cre/loxP system is an important technique that allows the bypass of embryonic lethal phenotypes and access to adult phenotypes. In this study, we generated a tamoxifen-inducible Cre-driver mouse strain for the purpose of widespread and...

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Detalles Bibliográficos
Autores principales: Ichise, Hirotake, Hori, Akiko, Shiozawa, Seiji, Kondo, Saki, Kanegae, Yumi, Saito, Izumu, Ichise, Taeko, Yoshida, Nobuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976237/
https://www.ncbi.nlm.nih.gov/pubmed/26923756
http://dx.doi.org/10.1538/expanim.15-0126