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Marked Sexual Dimorphism in the Role of the Ryanodine Receptor in a Model of Pain Chronification in the Rat

Hyperalgesic priming, an estrogen dependent model of the transition to chronic pain, produced by agonists at receptors that activate protein kinase C epsilon (PKCε), occurs in male but not in female rats. However, activation of second messengers downstream of PKCε, such as the ryanodine receptor, in...

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Detalles Bibliográficos
Autores principales:	Ferrari, Luiz F., Khomula, Eugen V., Araldi, Dionéia, Levine, Jon D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976309/ https://www.ncbi.nlm.nih.gov/pubmed/27499186 http://dx.doi.org/10.1038/srep31221

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