Pharmacokinetics and dose adjustment of etoposide administered in a medium-dose etoposide, cyclophosphamide and total body irradiation regimen before allogeneic hematopoietic stem cell transplantation

BACKGROUND: We investigated the pharmacokinetics of etoposide (ETP) to reduce the inter-individual variations of ETP concentrations in patients with acute leukemia who underwent allogeneic hematopoietic stem cell transplantation. We also carried out an in vivo study using rats to verify the dose adj...

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Detalles Bibliográficos
Autores principales: Tazawa, Yuki, Shigematsu, Akio, Kasashi, Kumiko, Sugita, Junichi, Endo, Tomoyuki, Kondo, Takeshi, Teshima, Takanori, Iseki, Ken, Sugawara, Mitsuru, Takekuma, Yoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976473/
https://www.ncbi.nlm.nih.gov/pubmed/27504190
http://dx.doi.org/10.1186/s40780-016-0052-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976473/
https://www.ncbi.nlm.nih.gov/pubmed/27504190
http://dx.doi.org/10.1186/s40780-016-0052-9

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