Cargando…
A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation
BACKGROUND: Small incision refractive lenticule extraction (SMILE) is an effective laser procedure that treats myopia. This research was to describe a novel approach to treat corneal ulcer or perforation using the corneal lenticules obtained from SMILE and to evaluate the safety and effectiveness of...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976570/ https://www.ncbi.nlm.nih.gov/pubmed/27453231 http://dx.doi.org/10.4103/0366-6999.186639 |
_version_ | 1782446895320268800 |
---|---|
author | Jiang, Yang Li, Ying Liu, Xiao-Wei Xu, Jing |
author_facet | Jiang, Yang Li, Ying Liu, Xiao-Wei Xu, Jing |
author_sort | Jiang, Yang |
collection | PubMed |
description | BACKGROUND: Small incision refractive lenticule extraction (SMILE) is an effective laser procedure that treats myopia. This research was to describe a novel approach to treat corneal ulcer or perforation using the corneal lenticules obtained from SMILE and to evaluate the safety and effectiveness of tectonic keratoplasty with femtosecond laser intrastromal lenticule (TEKIL). METHODS: A total of twenty patients (22 eyes) were monitored for at least 6 months and were assessed using slit lamp microscopy, optical coherence tomography, and best-corrected visual acuity (BCVA). Postoperative complications throughout the study period were recorded. RESULTS: Corneal ulcer in 14 patients (16 eyes) and corneal perforation in six patients (6 eyes) were treated with TEKIL. The patients were ten females and ten males, with a mean age of 58.5 ± 16.3 years (range: 16–81 years). In this study, the most causes of corneal ulcer or perforation were immunologic causes (54.5%). After TEKIL procedure, global integrity was achieved in all cases. No immune rejection or perforation was detected. The mean BCVA improved from 0.17 ± 0.20 preoperatively to 0.27 ± 0.25 postoperatively at the final follow-up (t = 2.095, P = 0.052). The postoperative BCVA improved in 12 eyes (54.5%) and maintained in nine eyes (40.9%). Vision function successfully maintained in all eyes (100%). In three cases, corneal ulcers were treated by reoperation of TEKIL at 3 months after the initial surgery for the reason that the residual corneal thickness was <250 μm. CONCLUSIONS: TEKIL seems to be an effective treatment for corneal ulcer and perforation in the condition of emergency and donor shortage. |
format | Online Article Text |
id | pubmed-4976570 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49765702016-08-25 A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation Jiang, Yang Li, Ying Liu, Xiao-Wei Xu, Jing Chin Med J (Engl) Original Article BACKGROUND: Small incision refractive lenticule extraction (SMILE) is an effective laser procedure that treats myopia. This research was to describe a novel approach to treat corneal ulcer or perforation using the corneal lenticules obtained from SMILE and to evaluate the safety and effectiveness of tectonic keratoplasty with femtosecond laser intrastromal lenticule (TEKIL). METHODS: A total of twenty patients (22 eyes) were monitored for at least 6 months and were assessed using slit lamp microscopy, optical coherence tomography, and best-corrected visual acuity (BCVA). Postoperative complications throughout the study period were recorded. RESULTS: Corneal ulcer in 14 patients (16 eyes) and corneal perforation in six patients (6 eyes) were treated with TEKIL. The patients were ten females and ten males, with a mean age of 58.5 ± 16.3 years (range: 16–81 years). In this study, the most causes of corneal ulcer or perforation were immunologic causes (54.5%). After TEKIL procedure, global integrity was achieved in all cases. No immune rejection or perforation was detected. The mean BCVA improved from 0.17 ± 0.20 preoperatively to 0.27 ± 0.25 postoperatively at the final follow-up (t = 2.095, P = 0.052). The postoperative BCVA improved in 12 eyes (54.5%) and maintained in nine eyes (40.9%). Vision function successfully maintained in all eyes (100%). In three cases, corneal ulcers were treated by reoperation of TEKIL at 3 months after the initial surgery for the reason that the residual corneal thickness was <250 μm. CONCLUSIONS: TEKIL seems to be an effective treatment for corneal ulcer and perforation in the condition of emergency and donor shortage. Medknow Publications & Media Pvt Ltd 2016-08-05 /pmc/articles/PMC4976570/ /pubmed/27453231 http://dx.doi.org/10.4103/0366-6999.186639 Text en Copyright: © 2016 Chinese Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Jiang, Yang Li, Ying Liu, Xiao-Wei Xu, Jing A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation |
title | A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation |
title_full | A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation |
title_fullStr | A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation |
title_full_unstemmed | A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation |
title_short | A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation |
title_sort | novel tectonic keratoplasty with femtosecond laser intrastromal lenticule for corneal ulcer and perforation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976570/ https://www.ncbi.nlm.nih.gov/pubmed/27453231 http://dx.doi.org/10.4103/0366-6999.186639 |
work_keys_str_mv | AT jiangyang anoveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT liying anoveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT liuxiaowei anoveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT xujing anoveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT jiangyang noveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT liying noveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT liuxiaowei noveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation AT xujing noveltectonickeratoplastywithfemtosecondlaserintrastromallenticuleforcornealulcerandperforation |