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Association of Anti-VEGF Injections with Progression of Geographic Atrophy
Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976793/ https://www.ncbi.nlm.nih.gov/pubmed/27528805 http://dx.doi.org/10.4137/OED.S38863 |
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author | Enslow, Ryan Bhuvanagiri, Sai Vegunta, Sravanthi Cutler, Benjamin Neff, Michael Stagg, Brian |
author_facet | Enslow, Ryan Bhuvanagiri, Sai Vegunta, Sravanthi Cutler, Benjamin Neff, Michael Stagg, Brian |
author_sort | Enslow, Ryan |
collection | PubMed |
description | Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA. |
format | Online Article Text |
id | pubmed-4976793 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-49767932016-08-15 Association of Anti-VEGF Injections with Progression of Geographic Atrophy Enslow, Ryan Bhuvanagiri, Sai Vegunta, Sravanthi Cutler, Benjamin Neff, Michael Stagg, Brian Ophthalmol Eye Dis Short Review Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA. Libertas Academica 2016-08-07 /pmc/articles/PMC4976793/ /pubmed/27528805 http://dx.doi.org/10.4137/OED.S38863 Text en © 2016 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License. |
spellingShingle | Short Review Enslow, Ryan Bhuvanagiri, Sai Vegunta, Sravanthi Cutler, Benjamin Neff, Michael Stagg, Brian Association of Anti-VEGF Injections with Progression of Geographic Atrophy |
title | Association of Anti-VEGF Injections with Progression of Geographic Atrophy |
title_full | Association of Anti-VEGF Injections with Progression of Geographic Atrophy |
title_fullStr | Association of Anti-VEGF Injections with Progression of Geographic Atrophy |
title_full_unstemmed | Association of Anti-VEGF Injections with Progression of Geographic Atrophy |
title_short | Association of Anti-VEGF Injections with Progression of Geographic Atrophy |
title_sort | association of anti-vegf injections with progression of geographic atrophy |
topic | Short Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976793/ https://www.ncbi.nlm.nih.gov/pubmed/27528805 http://dx.doi.org/10.4137/OED.S38863 |
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