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Association of Anti-VEGF Injections with Progression of Geographic Atrophy

Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD i...

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Autores principales: Enslow, Ryan, Bhuvanagiri, Sai, Vegunta, Sravanthi, Cutler, Benjamin, Neff, Michael, Stagg, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976793/
https://www.ncbi.nlm.nih.gov/pubmed/27528805
http://dx.doi.org/10.4137/OED.S38863
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author Enslow, Ryan
Bhuvanagiri, Sai
Vegunta, Sravanthi
Cutler, Benjamin
Neff, Michael
Stagg, Brian
author_facet Enslow, Ryan
Bhuvanagiri, Sai
Vegunta, Sravanthi
Cutler, Benjamin
Neff, Michael
Stagg, Brian
author_sort Enslow, Ryan
collection PubMed
description Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA.
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spelling pubmed-49767932016-08-15 Association of Anti-VEGF Injections with Progression of Geographic Atrophy Enslow, Ryan Bhuvanagiri, Sai Vegunta, Sravanthi Cutler, Benjamin Neff, Michael Stagg, Brian Ophthalmol Eye Dis Short Review Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA. Libertas Academica 2016-08-07 /pmc/articles/PMC4976793/ /pubmed/27528805 http://dx.doi.org/10.4137/OED.S38863 Text en © 2016 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Short Review
Enslow, Ryan
Bhuvanagiri, Sai
Vegunta, Sravanthi
Cutler, Benjamin
Neff, Michael
Stagg, Brian
Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_full Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_fullStr Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_full_unstemmed Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_short Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_sort association of anti-vegf injections with progression of geographic atrophy
topic Short Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976793/
https://www.ncbi.nlm.nih.gov/pubmed/27528805
http://dx.doi.org/10.4137/OED.S38863
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