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Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice

OBJECTIVE: Obesity increases morbidity and resource utilization in sepsis patients. Sepsis transitions from early/hyper-inflammatory to late/hypo-inflammatory phase. Majority of sepsis-mortality occurs during the late sepsis; no therapies exist to treat late sepsis. In lean mice, we have shown that...

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Detalles Bibliográficos
Autores principales:	Wang, Xianfeng, Buechler, Nancy L., Martin, Ayana, Wells, Jonathan, Yoza, Barbara, McCall, Charles E., Vachharajani, Vidula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976857/ https://www.ncbi.nlm.nih.gov/pubmed/27500833 http://dx.doi.org/10.1371/journal.pone.0160431

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